Mycoplasma Hominis Treatment

What is the drug of choice for Mycoplasma Hominis Treatment?

Medication is chosen based on efficacy, possible side effects it can cause, as well as the pregnancy status and complications already caused by Mycoplasma.

Despite the high chance of resistance, the drug of choice for treating Mycoplasma Hominis is doxycycline 100 mg twice daily for 7 days.

If mycoplasma caused PID (pelvic inflammatory disease), the duration of treatment with Doxycycline is longer -14 days. [1, 4] Case Report: Double trouble: a rare case of successfully treated Mycoplasma hominis and Pseudomonas aeruginosa co-infection
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183579/
Prevalence and Antimicrobial Susceptibility of Mycoplasma hominis and Ureaplasma Species in Nonpregnant Female Patients in South Korea Indicate an Increasing Trend of Pristinamycin-Resistant Isolates
https://pubmed.ncbi.nlm.nih.gov/32718969/

For pregnant people, the medication of choice is Clindamycin. [4] Prevalence and Antimicrobial Susceptibility of Mycoplasma hominis and Ureaplasma Species in Nonpregnant Female Patients in South Korea Indicate an Increasing Trend of Pristinamycin-Resistant Isolates https://pubmed.ncbi.nlm.nih.gov/32718969/

Moxifloxacin is used only in resistant cases due to significant side effects.

When is Mycoplasma treatment advised?

Mycoplasma treatment (similar to Ureaplasma)is advised when the test is positive, and the person is symptomatic at the same time. We treat positive tests alone if the person has a low immune system (HIV, cancer, taking medication to suppress the immune system).

Do sexual partners need to be tested or treated?

The testing and treatment for the partner is advised if:

Is the test of cure necessary?

A test of cure is necessary if:

When the test of cure can be done?

Mycoplasma Hominis test of cure can be done 21 days after finishing the treatment regimen.