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History

What caused the rash?

People contract chancroid and herpes similarly: infection is transmitted via skin-to-skin contact. Therefore, this is not a differentiating factor.

How soon do the symptoms appear?

It takes slightly longer for chancroid to appear.

The herpes incubation period is very short (2–4 days on average), while the chancroid incubation period lasts 5–7 days.

How are symptoms evolving?

There is a significant difference in how these conditions progress over time.

Unlike a herpes skin flare-up, preceded by prodrome symptoms (flu-like symptoms such as fever and chills) and “nerve pain,” chancroid has no preceding signs and symptoms.

Both conditions can present as a sore, but unlike herpes skin lesions, which transform into sores eventually (they start as a red skin patch that turns into bumps, blisters, and then sores), chancroid starts as a sore that over time gets bigger and deeper with significant discharge. Both conditions can present as a sore, but unlike herpes skin lesions, which transform to sores eventually (they start as a red skin patch that turns into bumps, blisters, and then sores), chancroid starts as a sore that over time gets bigger and deeper with significant discharge. [1, 4] Genital Herpes – CDC Detailed Fact Sheet
https://www.cdc.gov/std/herpes/stdfact-herpes-detailed.htm
Chancroid
https://www.cdc.gov/immigrantrefugeehealth/guidelines/domestic/sexually-transmitted-diseases/chancroid.html

The skin lesions in both conditions are painful, but chancroid presents with significantly more painful and enlarged lymph nodes. The lymph nodes eventually become purulent (meaning they produce a lot of pus). [2, 5] Genital Herpes Symptoms, Pictures, and Treatment
https://www.webmd.com/genital-herpes/ss/slideshow-genital-herpes
Chancroid
https://dermnetnz.org/topics/chancroid

The healing time for herpes is much shorter (1 week on average) compared to chancroid, which takes 8 weeks to heal.

Unlike herpes, which heals without scarring, chancroid can form a scar if left untreated.

These pictures show the differences between chancroid and herpes.

Warning

Contains sensitive content

View Photos

Herpes

Herpes

Chancroid

Chancroid

Visual exam

What do the lesions look like?

Herpes present with multiple small sores (2–3 mm across) clustered on the same red base. [3] Genital herpes: Overview https://www.ncbi.nlm.nih.gov/books/NBK525769/ A chancroid sore is much larger (10–20 mm); it is formed from multiple sores. [4] Chancroid
https://www.cdc.gov/immigrantrefugeehealth/guidelines/domestic/sexually-transmitted-diseases/chancroid.html

How much skin penetration is involved?

Herpes, unlike chancroid, affects only very superficial skin layers. A chancroid sore is deep; it penetrates the entire skin thickness.

What is the discharge like?

Discharge is a very important differentiating factor between herpes and chancroid lesions. Herpes can have minimal discharge for a short time. On the other hand, a chancroid sore is very purulent—that is, it produces a lot of pus. It can bleed easily as well.

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